- Route: Pob. Teniente Merino – La Reina, via Av. San Pablo (Pudahuel and Lo Prado), Matucana, the Alameda from Estación Central, Av. General Bustamante, Dublé Almeyda (Ñuñoa) and Av. Larraín to Av. Diagonal Las Torres.
- Services: regular 422 (35.7 km) and 422c, a short service Teniente Merino – Metro San Pablo, on weekday mornings only.
- Hours: the 422, every day from 05:30 to 00:00 (first and last departure); the 422c, Monday to Friday from 05:30 to 09:30.
- Frequency: in the morning peak (07:00–09:00) the shortest scheduled interval is 8 minutes on the 422 and 13 minutes on the 422c.
- Fare: CLP 795 with the tarjeta bip! (adult bus fare, in force since 22 February 2026), with transfers included within 120 minutes.
Bus 422 route map
Outbound (blue) and return (orange) route and stops of the main service, from DTPM GTFS. Map: © OpenStreetMap contributors.
Bus 422 services
| Service | Route | Service | Km | Frequency (peak) |
|---|---|---|---|---|
| 422 | Pob. Teniente Merino – La Reina | Regular | 35.7 | ≤ 8 min |
| 422c | Pob. Teniente Merino – (M) San Pablo | Short | 7.5 | ≤ 13 min |
Services, routes and distances from the current operating programme of Santiago’s public transport authority (DTPM GTFS). The service code is shown on the bus sign.
Stops of service 422c · Pob. Teniente Merino – (M) San Pablo
- 1Los Maitenes esq. Río Itata
- 2Río Itata esq. Av. J. Guzmán Riesco
- 3CESFAM Cardenal R.Silva Henríquez
- 4El Tranque esq. Av. José J. Pérez
- 5Río Viejo Sur esq. San Juan Valdés
- 6Av. José J. Pérez esq. Pasaje Riñihue
- 7Av. José J. Pérez esq. Rupanco
- 8Av. José J. Pérez esq. Federico Errázuriz
- 9Federico Errázuriz esq. Av. San Daniel
- 10Federico Errázuriz esq. Av. San Francisco
- 11Federico Errázuriz esq. Avenida Mapocho
- 12Consultorio Pudahuel -Poniente
- 13Parroquia San Luis
- 14Santa Victoria – San Pablo
- 15Avenida San Pablo esq. Sargento Aldea
- 16San Pablo – La Estrella
- 17Liceo C87
- 18Municipalidad de Pudahuel
- 19(M) Pudahuel
- 20Villa Los Maitenes
- 21Villa Los Poetas
- 22Las Torres – San Pablo
- 23Avenida San Pablo esq. Gral. J. Buendía
- 24(M) San Pablo
Bus 422 timetable by day
| Service | Monday–Friday | Saturday | Sunday & holidays | Full trip |
|---|---|---|---|---|
| 422 | 05:30–00:00 102 departures |
05:30–00:00 70 departures |
05:30–00:00 67 departures |
≈ 170 min |
| 422c | 05:30–09:30 19 departures |
no service | no service | ≈ 27 min |
First and last departure from the start of the route, approximate number of departures and trip time from DTPM’s current operating programme. They may change due to detours: check the Red app or the bus stop sign.
Stops of service 422 (105, outbound)
- 1Río Clarillo esq. Río Trancura
- 2Los Maitenes esq. Río Refugio
- 3Los Maitenes esq. Boulevard Sur
- 4Los Maitenes esq. Río Itata
- 5Río Itata esq. Av. J. Guzmán Riesco
- 6CESFAM Cardenal R.Silva Henríquez
- 7El Tranque esq. Av. José J. Pérez
- 8Río Viejo Sur esq. San Juan Valdés
- 9Av. José J. Pérez esq. Pasaje Riñihue
- 10Av. José J. Pérez esq. Rupanco
- 11Av. José J. Pérez esq. Federico Errázuriz
- 12Federico Errázuriz esq. Av. San Daniel
- 13Federico Errázuriz esq. Av. San Francisco
- 14Federico Errázuriz esq. Avenida Mapocho
- 15Consultorio Pudahuel -Poniente
- 16Parroquia San Luis
- 17Santa Victoria – San Pablo
- 18Avenida San Pablo esq. Sargento Aldea
- 19San Pablo – La Estrella
- 20Liceo C87
- 21Municipalidad de Pudahuel
- 22(M) Pudahuel
- 23Villa Los Maitenes
- 24Villa Los Poetas
- 25Las Torres – San Pablo
- 26Avenida San Pablo esq. Gral. J. Buendía
- 27(M) San Pablo
- 28Municipalidad de Lo Prado
- 29(M) Lo Prado
- 30Avenida San Pablo esq. Casilda
- 31Villa Caupolicán
- 32(M) Blanqueado
- 33Escuela Inglaterra
- 34Radal – San Pablo
- 35Plaza Simón Bolívar
- 36Avenida San Pablo esq. Cruchaga Montt
- 37(M) Gruta de Lourdes
- 38Basílica de Lourdes
- 39Matucana – San Pablo
- 40Avenida Matucana esq. Santo Domingo
- 41(M) Quinta Normal
- 42Hospital San Juan de Dios
- 43Chacabuco esq. Romero
- 44(M) Estación Central
- 45(M) Unión Latinoamericana
- 46(M) República
- 47(M) Los Héroes
- 48(M) La Moneda
- 49(M) Universidad de Chile
- 50(M) Santa Lucía
- 51(M) Universidad Católica
- 52Plaza Italia
- 53Barón P. de Coubertin esq. Av.Vicuña Mackenna
- 54(M) Parque Bustamante
- 55Av. General Bustamante esq. Malaquías Concha
- 56(M) Irarrázaval
- 57(M) Irarrázaval
- 58(M) Irarrázaval
- 59Matta Oriente Altura del 500
- 60Dublé Almeyda esq. Avenida Salvador
- 61Dublé Almeyda esq. José M. Infante
- 62(M) Mons. Eyzaguirre
- 63Dublé Almeyda esq. H. Covarrubias
- 64Dublé Almeyda esq. Campos de Deportes
- 65(M) Ñuñoa
- 66Dublé Almeyda esq. Los 3 Antonios
- 67Dublé Almeyda esq. Exequiel Fernández
- 68(M) Chile España
- 69Plaza Ñuñoa
- 70Dublé Almeyda esq. Brown Sur
- 71Dublé Almeyda esq. Los Jardines
- 72Dublé Almeyda esq. Juan Moya Morales
- 73Dublé Almeyda esq. Alc. J. Monckeberg
- 74Dublé Almeyda esq. Ramón Cruz Montt
- 75Dublé Almeyda esq. Los Aliaga
- 76Dublé Almeyda esq. Av. A. Vespucio
- 77Av. Américo Vespucio esq. Blest Gana
- 78Blest Gana esq. Paula Jaraquemada
- 79Blest Gana esq. Carlos Nazarit
- 80Blest Gana esq. Julio Montebruno
- 81Blest Gana esq. Avenida Tobalaba
- 82(M) Fernando Castillo Velasco
- 83Avenida Larrain esq. Los Maitenes
- 84Avenida Larrain esq. Los Litres
- 85Avenida Larrain esq. Pepe Vila
- 86Avenida Larrain esq. El Olmo
- 87Aeródromo Tobalaba
- 88Avenida Larrain esq. Jorge Alessandri
- 89Hospital Militar
- 90Andacollo esq. Pasaje 8
- 91Andacollo esq. Pasaje 12
- 92Mamiña esq. Quillagua
- 93Parinacota esq. Pasaje 3
- 94Parinacota esq. Avenida Larraín
- 95Colegio Las Américas
- 96Av. Las Perdices esq. Minerva Poblete
- 97Av. Las Perdices esq. Talinay
- 98Club de Campo Militar
- 99Av. Las Perdices esq. Av. José Arrieta
- 100Av. Diagonal Las Torres esq. Los Arroyuelos
- 101Av. Diagonal Las Torres esq. Río Lauca
- 102Av. Diagonal Las Torres esq. Los Baqueanos
- 103Av. Diagonal Las Torres esq. Alvaro Casanova
- 104Av. Diagonal Las Torres esq. Avenida Grecia
- 105Av. Diagonal Las Torres esq. Álvaro Casanova
Stops of service 422 (101, return)
- 1Av. Diagonal Las Torres esq. Álvaro Casanova
- 2Av. Diagonal Las Torres esq. Quebrada de Taltal
- 3Av. Diagonal Las Torres esq. El Parque
- 4Av. Diagonal Las Torres esq. Río Lauca
- 5Av. Diagonal Las Torres esq. Las Vertientes
- 6Av. Diagonal Las Torres esq. Av. José Arrieta
- 7Club de Campo Militar
- 8Talinay esq. Caquena
- 9Talinay esq. Quillagua
- 10Quillagua esq. Mamiña
- 11Quillagua esq. Pasaje 6
- 12Quillagua esq. Castillo Velasco
- 13Avenida Larrain esq. Andacollo
- 14Hospital Militar
- 15Avenida Larrain esq. Carlos Ossandón
- 16Aeródromo Tobalaba
- 17Avenida Larrain esq. V. Pérez Rosales
- 18Avenida Larrain esq. Valladolid
- 19Avenida Larrain esq. Palmas de Mallorca
- 20(M) Fernando Castillo Velasco
- 21Avenida Larrain esq. Rubén Darío-Norte
- 22Avenida Larrain esq. J. Carrera Nte.
- 23(M) Plaza Egaña
- 24Plaza Los Guindos
- 25(M) Villa Frei
- 26Avenida Irarrázaval esq. Ortúzar
- 27Casa de La Cultura Ñuñoa
- 28Avenida Irarrázaval esq. Pedro Torres
- 29Plaza Ñuñoa
- 30(M) Chile España
- 31(M) Ñuñoa
- 32Avenida Irarrázaval esq. Marchant Pereira
- 33Irarrázaval – Campos del Deporte
- 34(M) Mons. Eyzaguirre
- 35Avenida Irarrázaval esq. José M. Infante
- 36Irarrázaval – Salvador
- 37Avenida Irarrázaval esq. Avenida Condell
- 38(M) Irarrázaval
- 39(M) Irarrázaval
- 40Avenida 10 de Julio esq. Avenida Portugal
- 41Portugal esq. Argomedo
- 42Portugal esq. Santa Isabel
- 43Claustro Del 900
- 44Posta Central
- 45FAU Univers. de Chile
- 46Hospital Univers. Católica
- 47(M) Universidad Católica
- 48(M) Santa Lucía
- 49(M) Universidad de Chile
- 50(M) La Moneda
- 51(M) Los Héroes
- 52(M) República
- 53(M) Unión Latinoamericana
- 54(M) Estación Central
- 55Liceo Iasura Dinator
- 56Hospital San Juan de Dios
- 57(M) Quinta Normal
- 58Santo Domingo – Matucana
- 59Avenida Matucana esq. Rosas
- 60Martínez de Rozas esq. Patricio Lynch
- 61Martínez de Rozas esq. Rivas Vicuña
- 62Martínez de Rozas esq. Villasana
- 63Martínez de Rozas esq. Av. Coronel Robles
- 64Martínez de Rozas esq. Antonio Ebner
- 65Santa Genoveva esq. Alejandro Fierro
- 66Santa Genoveva esq. Av.San Pablo
- 67Plaza Simón Bolívar
- 68Radal – San Pablo
- 69(M) Blanqueado
- 70Villa Caupolicán
- 71Avenida San Pablo esq. Necochea
- 72(M) Lo Prado
- 73Municipalidad de Lo Prado
- 74(M) San Pablo
- 75Avenida San Pablo esq. Las Madreselvas
- 76Las Torres – San Pablo
- 77Villa Los Poetas
- 78Villa Los Maitenes
- 79(M) Pudahuel
- 80Municipalidad de Pudahuel
- 81Liceo C87
- 82San Pablo – La Estrella
- 83Avenida San Pablo esq. Sargento Aldea
- 84Santa Victoria – San Pablo
- 85Parroquia San Luis
- 86Consultorio Pudahuel -Poniente
- 87Federico Errázuriz esq. Avenida Mapocho
- 88Federico Errázuriz esq. Av. San Francisco
- 89Federico Errázuriz esq. Forestales
- 90Federico Errázuriz esq. Av. San Daniel
- 91Avenida San Daniel esq. Serrano
- 92Serrano esq. Av. José J. Pérez
- 93Av. José J. Pérez esq. Villarrica
- 94Río Viejo Sur esq. El Tranque
- 95CESFAM Cardenal R.Silva Henríquez
- 96Río Itata esq. Av. J. Guzmán Riesco
- 97Río Itata esq. Los.Maitenes Pte.
- 98Los Maitenes esq. Bvard.Aeropuerto
- 99Los Maitenes esq. Río Refugio
- 100Salar de Atacama esq. Los. Maitenes-Oriente
- 101Río Clarillo esq. Río Trancura
Route 422 is a Red Movilidad bus (locally a “micro”), part of the system formerly known as Transantiago, that links the Población Teniente Merino in the west with La Reina in the east. It is a long route: 35.7 km outbound via Av. San Pablo, the Alameda, Ñuñoa and Av. Larraín. In the ranking of the most used services of 2025 published by Red it came eighth, with an average of 19,212 transactions per working day between January and November, listed as a Pudahuel – Peñalolén service. People also search for it as “micro 422” or “422 recorrido”. Below you will find the route by section, the services, the timetable and how to see where the bus is.
Route 422: from Teniente Merino to La Reina
Teniente Merino and Pudahuel. The 422 starts at Río Clarillo and Río Trancura, passes Los Maitenes, Río Itata, Av. J. Guzmán Riesco and CESFAM Cardenal R. Silva Henríquez, and continues via El Tranque, Río Viejo Sur, Av. José J. Pérez and Federico Errázuriz to the Consultorio Pudahuel Poniente.
Av. San Pablo. Along Avenida San Pablo it passes the Parroquia San Luis, Liceo C87, the Municipalidad de Pudahuel and Pudahuel station, Villa Los Maitenes, Villa Los Poetas, San Pablo station, the Municipalidad de Lo Prado, the Lo Prado and Blanqueado stations, Plaza Simón Bolívar and Gruta de Lourdes station, next to the Basílica de Lourdes.
Matucana and the Alameda. It goes down Avenida Matucana to Quinta Normal station and the Hospital San Juan de Dios, and via Chacabuco reaches the Alameda at Estación Central. It runs the central axis: Unión Latinoamericana, República, Los Héroes, La Moneda, Universidad de Chile, Santa Lucía and Universidad Católica, up to Plaza Italia.
Bustamante and Ñuñoa. From Plaza Italia it continues via Barón P. de Coubertin, Parque Bustamante and Av. General Bustamante to Irarrázaval, and turns onto Dublé Almeyda: it passes the Monseñor Eyzaguirre, Ñuñoa and Chile España stations and the Plaza Ñuñoa, up to Av. Américo Vespucio.
La Reina. The final stretch runs via Blest Gana to Avenida Tobalaba and Fernando Castillo Velasco station, then along Avenida Larraín, with stops next to the Aeródromo Tobalaba and the Hospital Militar. It then passes Andacollo, Mamiña, Parinacota, Colegio Las Américas, Av. Las Perdices and the Club de Campo Militar, and ends at Av. Diagonal Las Torres and Álvaro Casanova.
The return trip changes quite a lot in the east: from Av. Larraín it passes the Plaza Egaña and Villa Frei stations and comes back along Avenida Irarrázaval (Casa de la Cultura Ñuñoa, Plaza Ñuñoa, Chile España, Ñuñoa), Av. 10 de Julio and Portugal, with stops at the Posta Central and the Hospital of the Universidad Católica, to the Alameda. In the west it goes up Matucana and Martínez de Rozas and returns to Av. San Pablo.
422 services and variants
The 422c is the Teniente Merino – Metro San Pablo short service. It follows the same route as the 422 from Los Maitenes, via José J. Pérez, Federico Errázuriz and Av. San Pablo, passing Pudahuel station, and ends at San Pablo station. It is 7.5 km long with 27 scheduled minutes. It runs Monday to Friday only, from 05:30 to 09:30, with about 19 departures and a minimum interval of 13 minutes at peak time. It is designed to get you to the Metro in the morning; to continue to the centre or Ñuñoa you need the regular 422 or a transfer.
Route 422 timetable
According to the current DTPM operating schedule (October 2026), the 422 runs every day from 05:30 to 00:00 (first and last scheduled departures). On weekdays it has about 102 departures, on Saturday about 70 and on Sunday about 67. It is not a 24-hour service: after midnight there are no departures until 05:30.
In the morning peak (07:00 to 09:00) on a weekday, the shortest scheduled interval is 8 minutes on the 422 and 13 minutes on the 422c. At weekends only the regular 422 runs.
How long the 422 takes
According to the operating schedule, a full outbound trip from Teniente Merino to La Reina has a scheduled time of 170 minutes for 35.7 km, almost three hours. That is why it makes sense to think of the trip in sections, for example Pudahuel to the centre or the Alameda to Ñuñoa. Work out your trip with the planner in the App Red or on red.cl, and allow extra time at peak hours.
Bus stops and Metro connections
The 422 has 105 stops outbound and 101 on the return, and passes 22 Metro stations across both directions. On Av. San Pablo: Pudahuel, San Pablo, Lo Prado, Blanqueado and Gruta de Lourdes. On Matucana: Quinta Normal. On the Alameda: Estación Central, Unión Latinoamericana, República, Los Héroes, La Moneda, Universidad de Chile, Santa Lucía and Universidad Católica. After that: Parque Bustamante, Irarrázaval, Monseñor Eyzaguirre, Ñuñoa, Chile España and Fernando Castillo Velasco. On the return it adds Plaza Egaña and Villa Frei.
422 stop on Av. San Pablo and destination of the 422c short service.
Stop on Dublé Almeyda, next to Chile España station; the return trip uses Av. Irarrázaval.
Stop on Avenida Larraín in La Reina, near the Aeródromo Tobalaba.
How to find out where the 422 bus is
To see how long until the next 422, use the App Red (in the app stores, “Red Metropolitana de Movilidad”), which is free and has an arrival predictor for each bus stop (paradero). You can also use “¿Cuándo llega?” on red.cl. Enter the bus stop code, printed on the stop sign: it starts with P, followed by a zone letter and a number. On weekday mornings on Av. San Pablo, check whether the predictor shows a 422 or a 422c: the short service ends at Metro San Pablo.
Fare and tarjeta bip!
Since 22 February 2026 the adult fare on Red buses is CLP 795 at any time, including on the 422c. Secondary and higher-education students pay CLP 260 with the TNE, primary school pupils ride free and seniors with the bip! Adulto Mayor pay CLP 390. You can pay with the tarjeta bip! (it costs CLP 1,550) or with bip!QR from the App Red and other apps.
A single payment covers up to two transfers (three legs) within 120 minutes of the first validation, as long as you do not repeat the same bus route. There is no extra charge between buses; if you transfer from the 422 to the Metro during peak hours, you pay the difference up to CLP 895.
Tips for travelling on the 422
- With almost three scheduled hours end to end, on long journeys it pays to switch to the Metro at San Pablo, Estación Central or on the Alameda.
- In Ñuñoa the outbound bus uses Dublé Almeyda and the return uses Av. Irarrázaval: check which street to wait on.
- The last 422 leaves at 00:00; if you are coming back later, plan another route in the App Red.
- If you only need to get from Teniente Merino to the Metro in the morning, the 422c is shorter.