- Route: Maipú – San Carlos de Apoquindo, via Av. Los Pajaritos, the whole Alameda, Providencia, Av. Apoquindo in Las Condes and Camino El Alba.
- Services: regular 421 (37.3 km) and 421c, a short loop service San Carlos de Apoquindo – Metro Los Dominicos, on weekdays only.
- Hours: the 421 runs 24 hours a day, every day; the 421c, Monday to Friday from 06:30 to 20:30.
- Frequency: in the morning peak (07:00–09:00) the shortest scheduled interval is 5 minutes on the 421 and 18 minutes on the 421c.
- Fare: CLP 795 with the tarjeta bip! (adult bus fare, in force since 22 February 2026), with transfers included within 120 minutes.
Bus 421 route map
Outbound (blue) and return (orange) route and stops of the main service, from DTPM GTFS. Map: © OpenStreetMap contributors.
Bus 421 services
| Service | Route | Service | Km | Frequency (peak) |
|---|---|---|---|---|
| 421 | Maipú – San Carlos De Apoquindo | Regular | 37.3 | ≤ 5 min |
| 421c | San Carlos De Apoquindo – (M) Los Dominicos | Short | 12 | ≤ 18 min |
Services, routes and distances from the current operating programme of Santiago’s public transport authority (DTPM GTFS). The service code is shown on the bus sign.
Stops of service 421c · San Carlos De Apoquindo – (M) Los Dominicos
- 1Camino El Alba esq. Avenida La Plaza
- 2Scuola Italiana
- 3Avenida La Plaza esq. Rep. de Honduras
- 4Sn. C. de Apoquindo esq. Camino Las Flores
- 5Cam. Las Flores esq. Cam. Las Vertientes
- 6Cam. Las Flores esq. Fco. Bulnes Correa
- 7Cam. Las Flores esq. Camino Otoñal
- 8Cam. Las Flores esq. Camino La Fuente
- 9Cam. Las Flores esq. Camino Piedraroja
- 10Cam. Las Flores esq. Camino Mirasol
- 11Cam. Las Flores esq. Cam. del Algarrobo
- 12Cam. del Algarrobo Altura del 1500
- 13Cam. del Algarrobo Altura del 1300
- 14Camino del Algarrobo esq. Los Pintores
- 15Camino El Alba esq. Vital Apoquindo
- 16Camino El Alba esq. Cam. del Observatorio
- 17Camino El Alba esq. Cam. del Observatorio
- 18Avenida Paul Harris esq. General Blanche
- 19General Blanche esq. Círculo Apolo
- 20(M) Los Dominicos
- 21Camino El Alba esq. Cardenal Newman
- 22Camino El Alba esq. Av. Paul Harris
- 23Camino El Alba esq. Vital Apoquindo
- 24Camino El Alba esq. Cam. del Algarrobo
- 25Camino del Algarrobo esq. Los Pintores
- 26Cam. del Algarrobo Altura del 1300
- 27Cam. del Algarrobo Altura del 1500
- 28Camino del Algarrobo esq. Circun. Las Flores
- 29Circ. Las Flores esq. Camino Mirasol
- 30Cam. Las Flores esq. Camino Piedraroja
- 31Cam. Las Flores esq. Camino La Fuente
- 32Cam. Las Flores esq. Camino Otoñal
- 33Cam. Las Flores esq. Fco. Bulnes Correa
- 34Cam. Las Flores esq. Circun. Las Flores
- 35Cam. Las Flores esq. Sn. C. de Apoquindo
- 36Cam. Las Flores esq. Avenida La Plaza
- 37Scuola Italiana
Bus 421 timetable by day
| Service | Monday–Friday | Saturday | Sunday & holidays | Full trip |
|---|---|---|---|---|
| 421 | Runs 24 hours 118 departures · every 45 min at night |
Runs 24 hours 87 departures · every 135 min at night |
Runs 24 hours 69 departures · every 90 min at night |
≈ 106 min |
| 421c | 06:30–20:30 27 departures |
no service | no service | ≈ 46 min |
First and last departure from the start of the route, approximate number of departures and trip time from DTPM’s current operating programme. They may change due to detours: check the Red app or the bus stop sign.
Stops of service 421 (100, outbound)
- 1Terminal Las Acacias
- 2Av. El Conquistador esq. La Castellana
- 3Av. El Conquistador esq. Nueva San Martín
- 4CESFAM Dr. Carlos Godoy
- 5Av. Edo. Frei Montalva esq. La Galaxia
- 6Av. Edo. Frei Montalva esq. Avenida 4 Poniente
- 7Avenida 4 Poniente esq. Ignacio García S.
- 8Avenida 4 Poniente esq. Nueva San Martín
- 9Av. Nueva San Martín esq. Av. Las Naciones
- 10Av. Nueva San Martín esq. Ramón Barros Luco
- 11Boston College Nueva Sn. Martín
- 12Av. Nueva San Martín esq. El Olimpo
- 13Av. Nueva San Martín esq. Carlomagno
- 14Av. Nueva San Martín esq. Los Diamantes
- 15Av. Nueva San Martín esq. La Fortuna
- 16Santa Elena esq. Comarca
- 17Santa Elena esq. Avenida Sur
- 18El Carmen esq. Cunco
- 19El Carmen esq. Avenida Portales
- 20El Carmen esq. San José
- 21El Carmen esq. La Colonia
- 22Templo Votivo
- 23Templo Votivo
- 24(M) Plaza de Maipú
- 25Avenida Los Pajaritos esq. Luis Gandarillas
- 26Avenida Los Pajaritos esq. Av. Pérez Llona
- 27Avenida Los Pajaritos esq. Alhué
- 28(M) Santiago Bueras
- 29Paradero 14 Pajaritos
- 30(M) Del Sol
- 31Paradero 12 Pajaritos
- 32Colegio Santa María de Maipú
- 33(M) Monte Tabor
- 34Paradero 10 Pajaritos
- 35(M) Las Parcelas
- 36Paradero 8 Pajaritos
- 37Paradero 7 1/2 Pajaritos
- 38Paradero 7 Pajaritos
- 39Paradero 6 Pajaritos
- 40Paradero 5 1/2 Pajaritos
- 41Paradero 5 Pajaritos
- 42Paradero 4 Pajaritos
- 43Alameda esq. Pasaje El Lingue
- 44(M) Las Rejas
- 45(M) Ecuador
- 46Concón
- 47(M) San Alberto Hurtado
- 48(M) Universidad de Santiago
- 49San Borja
- 50(M) Estación Central
- 51(M) Unión Latinoamericana
- 52(M) República
- 53(M) Los Héroes
- 54(M) La Moneda
- 55(M) Universidad de Chile
- 56(M) Santa Lucía
- 57(M) Universidad Católica
- 58Plaza Italia
- 59Museo de Los Tajamares
- 60Parque Balmaceda
- 61(M) Salvador
- 62Torres de Tajamar
- 63(M) Manuel Montt
- 64(M) Pedro de Valdivia
- 65Guardia Vieja
- 66(M) Los Leones
- 67(M) Los Leones
- 68(M) Tobalaba
- 69(M) El Golf
- 70Municipalidad de Las Condes
- 71(M) Alcántara
- 72Cerro Navidad
- 73(M) Escuela Militar
- 74Omnium
- 75Avenida Apoquindo esq. Rosa O'Higgins
- 76Avenida Apoquindo esq. Luis Zegers
- 77(M) Manquehue
- 78Avenida Apoquindo esq. E. Dell'Orto
- 79Estadio Italiano
- 80(M) Hernando de Magallanes
- 81INACAP Apoquindo
- 82Avenida Apoquindo esq. Torremolino
- 83(M) Los Dominicos
- 84Camino El Alba esq. Cardenal Newman
- 85Camino El Alba esq. Av. Paul Harris
- 86Camino El Alba esq. Vital Apoquindo
- 87Camino El Alba esq. Cam. del Algarrobo
- 88Camino del Algarrobo esq. Los Pintores
- 89Cam. del Algarrobo Altura del 1300
- 90Cam. del Algarrobo Altura del 1500
- 91Camino del Algarrobo esq. Circun. Las Flores
- 92Circ. Las Flores esq. Camino Mirasol
- 93Cam. Las Flores esq. Camino Piedraroja
- 94Cam. Las Flores esq. Camino La Fuente
- 95Cam. Las Flores esq. Camino Otoñal
- 96Cam. Las Flores esq. Fco. Bulnes Correa
- 97Cam. Las Flores esq. Circun. Las Flores
- 98Cam. Las Flores esq. Sn. C. de Apoquindo
- 99Cam. Las Flores esq. Avenida La Plaza
- 100Scuola Italiana
Stops of service 421 (105, return)
- 1Camino El Alba esq. Avenida La Plaza
- 2Scuola Italiana
- 3Avenida La Plaza esq. Rep. de Honduras
- 4Sn. C. de Apoquindo esq. Camino Las Flores
- 5Cam. Las Flores esq. Cam. Las Vertientes
- 6Cam. Las Flores esq. Fco. Bulnes Correa
- 7Cam. Las Flores esq. Camino Otoñal
- 8Cam. Las Flores esq. Camino La Fuente
- 9Cam. Las Flores esq. Camino Piedraroja
- 10Cam. Las Flores esq. Camino Mirasol
- 11Cam. Las Flores esq. Cam. del Algarrobo
- 12Cam. del Algarrobo Altura del 1500
- 13Cam. del Algarrobo Altura del 1300
- 14Camino del Algarrobo esq. Los Pintores
- 15Camino El Alba esq. Vital Apoquindo
- 16Camino El Alba esq. Cam. del Observatorio
- 17Camino El Alba esq. Cam. del Observatorio
- 18Camino El Alba esq. Waterloo
- 19Camino El Alba esq. Av. Padre A. Hurtado
- 20(M) Los Dominicos
- 21Avenida Apoquindo esq. Zanzíbar Pnte.
- 22INACAP Apoquindo
- 23(M) Hernando de Magallanes
- 24Avenida Apoquindo esq. General C. Urzúa
- 25Estadio Italiano
- 26(M) Manquehue
- 27(M) Manquehue
- 28(M) Manquehue
- 29Avenida Apoquindo esq. Warren Smith
- 30Omnium
- 31(M) Escuela Militar
- 32Cerro Navidad
- 33(M) Alcántara
- 34Municipalidad de Las Condes
- 35(M) El Golf
- 36Avenida Apoquindo esq. El Bosque Norte
- 37(M) Tobalaba
- 38Hospital Metropolitano
- 39(M) Los Leones
- 40(M) Pedro de Valdivia
- 41(M) Pedro de Valdivia
- 42Biblioteca de Providencia
- 43(M) Manuel Montt
- 44Torres de Tajamar
- 45(M) Salvador
- 46Parque Balmaceda
- 47Museo de Los Tajamares
- 48Plaza Italia
- 49(M) Universidad Católica
- 50(M) Santa Lucía
- 51(M) Universidad de Chile
- 52(M) La Moneda
- 53(M) La Moneda
- 54(M) Los Héroes
- 55(M) República
- 56(M) Unión Latinoamericana
- 57(M) Estación Central
- 58(M) Universidad de Santiago
- 59(M) San Alberto Hurtado
- 60Concón
- 61(M) Ecuador
- 62(M) Las Rejas
- 63Paradero 4 Pajaritos
- 64Paradero 5 Pajaritos
- 65Paradero 5 1/2 Pajaritos
- 66Paradero 6 Pajaritos
- 67Paradero 7 Pajaritos
- 68Paradero 7 1/2 Pajaritos
- 69Paradero 8 Pajaritos
- 70(M) Las Parcelas
- 71Paradero 10 Pajaritos
- 72(M) Monte Tabor
- 73Colegio Santa María de Maipú
- 74Paradero 12 Pajaritos
- 75(M) Del Sol
- 76Paradero 14 Pajaritos
- 77(M) Santiago Bueras
- 78Avenida Los Pajaritos esq. Centenario
- 79Avenida Los Pajaritos esq. Avenida Chile
- 80Avenida Los Pajaritos esq. Maipú
- 81Chacabuco esq. Manuel Rodríguez
- 82Chacabuco esq. Psje. Chacabuco
- 83San Martín esq. Cam. a Rinconada
- 84El Carmen esq. Carmen L. Correa
- 85El Carmen esq. San José
- 86El Carmen esq. Avenida Portales
- 87El Carmen esq. Avenida Sur
- 88Santa Elena esq. Nueva O'Higgins
- 89Santa Elena esq. Nueva San Martín
- 90Av. Nueva San Martín esq. La Fortuna
- 91Av. Nueva San Martín esq. Av. Padre A. Hurtado
- 92Av. Nueva San Martín esq. Río Eufrates
- 93Av. Nueva San Martín esq. El Olimpo
- 94Boston College Nueva Sn. Martín
- 95Av. Nueva San Martín esq. Univ. Católica
- 96Av. Nueva San Martín esq. Av. Las Naciones
- 97Av. Nueva San Martín esq. Avenida 4 Poniente
- 98Avenida 4 Poniente esq. Pdte. Frei Montalva
- 99Av. Edo. Frei Montalva esq. La Galaxia
- 100Av. Edo. Frei Montalva esq. Av. El Conquistador
- 101CESFAM Dr. Carlos Godoy
- 102Av. El Conquistador esq. Nueva San Martín
- 103Av. El Conquistador esq. Avenida Sur
- 104Av. El Conquistador esq. Avenida Portales
- 105Terminal Las Acacias
Route 421 is the bus (locally called a “micro”) that links Maipú with San Carlos de Apoquindo, in Las Condes, crossing Santiago from west to east along the Alameda. It is 37.3 km long outbound and is a Red Movilidad service, the system formerly known as Transantiago. It runs along Av. Los Pajaritos, the whole Alameda, Providencia and Av. Apoquindo, and operates 24 hours a day. Almost the whole trip runs alongside the Metro, with 28 stations on the way. Many people search for it as “micro 421” or “recorrido 421 mapa”. Here you have the route by section, the 421c short service, the timetable and how to find out where the bus is.
Route 421: from Maipú to San Carlos de Apoquindo
Maipú. The 421 starts at Terminal Las Acacias and runs along Av. El Conquistador, past the CESFAM Dr. Carlos Godoy, Av. Eduardo Frei Montalva and Avenida 4 Poniente. It continues along Av. Nueva San Martín (Las Naciones, Boston College, El Olimpo, La Fortuna), Santa Elena and El Carmen, passes the Templo Votivo and reaches Plaza de Maipú station.
Av. Los Pajaritos. From Plaza de Maipú it takes Avenida Los Pajaritos eastwards and follows its stop numbering from 14 down to 4, stopping at Santiago Bueras, Del Sol, Monte Tabor and Las Parcelas stations, until it joins the Alameda.
Alameda. It runs the whole central axis: Las Rejas, Ecuador, San Alberto Hurtado, Universidad de Santiago, Estación Central, Unión Latinoamericana, República, Los Héroes, La Moneda, Universidad de Chile, Santa Lucía and Universidad Católica, up to Plaza Italia.
Providencia. It passes the Museo de Los Tajamares, Parque Balmaceda and Torres de Tajamar, stopping at Salvador, Manuel Montt, Pedro de Valdivia, Guardia Vieja and Los Leones, up to Tobalaba station.
Av. Apoquindo and Las Condes. It continues along Avenida Apoquindo: El Golf, the Municipalidad de Las Condes, Alcántara, Cerro Navidad, Escuela Militar, Omnium, Manquehue, the Estadio Italiano, Hernando de Magallanes and INACAP Apoquindo, up to Los Dominicos station.
San Carlos de Apoquindo. The last stretch climbs Camino El Alba (Av. Paul Harris, Vital Apoquindo), Camino del Algarrobo and Camino Las Flores, and ends at the Scuola Italiana, next to Avenida La Plaza.
The return trip, signed Maipú, starts at Camino El Alba and Avenida La Plaza and follows the same axis in reverse; in Providencia it passes the Hospital Metropolitano and the Biblioteca de Providencia. In Maipú it leaves Av. Los Pajaritos via Chacabuco and San Martín, without stopping at Plaza de Maipú station, and goes back via El Carmen and Av. Nueva San Martín to Terminal Las Acacias.
421 services and variants
The 421c is a short loop service San Carlos de Apoquindo – Metro Los Dominicos. It leaves from Camino El Alba and Avenida La Plaza, runs along Camino Las Flores and Camino del Algarrobo, goes down Camino El Alba, Av. Paul Harris and General Blanche to Los Dominicos station and comes back through the same area to the Scuola Italiana. It is 12 km long in total and has 46 scheduled minutes.
It runs Monday to Friday only, from 06:30 to 20:30, with about 27 departures and a minimum interval of 18 minutes in the morning peak. It does not run on Saturday or Sunday. It is handy if you only need to get from San Carlos de Apoquindo to Metro Los Dominicos.
Route 421 timetable
According to the current DTPM operating schedule (October 2026), the 421 runs 24 hours a day, Monday to Sunday. It has about 118 departures on weekdays, about 87 on Saturday and about 69 on Sunday. In the early hours it keeps running at longer intervals: about 45 minutes on weekdays, about 135 minutes on Saturday and about 90 minutes on Sunday.
In the morning peak (07:00 to 09:00) on a weekday, the shortest scheduled interval is 5 minutes on the 421 and 18 minutes on the 421c.
How long the 421 takes
According to the operating schedule, a full outbound trip on the 421, from Maipú to San Carlos de Apoquindo, has a scheduled time of 106 minutes for 37.3 km. The 421c loop has 46 minutes for 12 km. These are reference times: allow extra time in peak hours, especially on the Alameda, in Providencia and on Apoquindo.
Bus stops and Metro connections
The 421 has 100 stops outbound and 105 on the return, and passes 28 Metro stations. In Maipú and on Av. Los Pajaritos: Plaza de Maipú (outbound only), Santiago Bueras, Del Sol, Monte Tabor and Las Parcelas. On the Alameda: Las Rejas, Ecuador, San Alberto Hurtado, Universidad de Santiago, Estación Central, Unión Latinoamericana, República, Los Héroes, La Moneda, Universidad de Chile, Santa Lucía and Universidad Católica. In Providencia: Salvador, Manuel Montt, Pedro de Valdivia, Los Leones and Tobalaba. On Apoquindo: El Golf, Alcántara, Escuela Militar, Manquehue, Hernando de Magallanes and Los Dominicos.
Start of the 421 in Maipú and end of the return trip.
Last station on the route and turning point of the 421c.
421 stop on El Carmen, just before Plaza de Maipú.
How to find out where the 421 bus is
To see how long until the next 421, use the App Red (in the app stores, “Red Metropolitana de Movilidad”), which is free and has an arrival predictor for each bus stop (paradero). You can also use “¿Cuándo llega?” on red.cl. Enter the bus stop code, printed on the stop sign: it starts with P, followed by a zone letter and a number. At the stops on Camino El Alba and Camino Las Flores, check whether the predictor shows a 421 or a 421c: the 421c only goes as far as Los Dominicos.
Fare and tarjeta bip!
Since 22 February 2026 the adult fare on Red buses is CLP 795 at any time, including on the 421c. Secondary and higher-education students pay CLP 260 with the TNE, primary school pupils ride free and seniors with the bip! Adulto Mayor pay CLP 390. You can pay with the tarjeta bip! (it costs CLP 1,550) or with bip!QR from the App Red and other apps.
A single payment covers up to two transfers (three legs) within 120 minutes of the first validation, as long as you do not repeat the same bus route. There is no extra charge between buses; if you transfer from the 421 to the Metro during peak hours, you pay the difference up to CLP 895.
Tips for travelling on the 421
- As the 421 runs alongside the Metro for almost the whole trip, you can switch to the train at any station on the Alameda or Apoquindo if the bus is slow.
- If you are only going from San Carlos de Apoquindo to the Metro, the 421c also works for you on weekdays.
- Towards Maipú, the return trip does not stop at Plaza de Maipú station: get off on Av. Los Pajaritos or stay on to El Carmen.
- In the early hours the interval is 45 to 135 minutes depending on the day: check the App Red before you walk to the stop.